Targeting Oxidative Stress in Central Nervous System Disorders
نویسندگان
چکیده
منابع مشابه
Oxidative Stress and the Central Nervous System.
Biochemical integrity of the brain is vital for normal functioning of the central nervous system (CNS). One of the factors contributing to cerebral biochemical impairment is a chemical process called oxidative stress. Oxidative stress occurs upon excessive free radical production resulting from an insufficiency of the counteracting antioxidant response system. The brain, with its high oxygen co...
متن کاملModeling oxidative stress in the central nervous system.
Oxidative stress is associated with the onset and pathogenesis of several prominent central nervous system disorders. Consequently, there is a pressing need for experimental methods for studying neuronal responses to oxidative stress. A number of techniques for modeling oxidative stress have been developed, including the use of inhibitors of the mitochondrial respiratory chain, depletion of end...
متن کاملADENOSINE IN THE CENTRAL NERVOUS SYSTEM
Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mecha...
متن کاملP124: Listeriosis in Central Nervous System
Listeriosis is one of the CNS inflammatory diseases which is happened majority in the form of sporadic. Listeriosis is ingested with the food. Infection occurrence in an exposed person depends on the number of organisms ingested, the virulence of the organisms strain and the individual condition. It is known that Listeriosis has decisive importance as an infection which the cellular immunodefen...
متن کاملDrugs in Central Nervous System Disorders
This book is the second in a series entitled "Clinical Pharmacology," edited by Murray Weiner. The volume contains six chapters, of varying quality, by authors who have been researchers in the area of neuropharmacology. The first chapter, "Centrally Acting Analgesics," is a well-documented (517 references), timely, and complete review of the newest research in the pharmacology and physiology of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Trends in Pharmacological Sciences
سال: 2016
ISSN: 0165-6147
DOI: 10.1016/j.tips.2016.06.007